Engineering and evaluating drug delivery particles in microfluidic devices

M Björnmalm; Y Yan; F Caruso

Journal article

Engineering and evaluating drug delivery particles in microfluidic devices

M Björnmalm, Y Yan, F Caruso

Journal of Controlled Release | Published : 2014

DOI: 10.1016/j.jconrel.2014.04.030

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Abstract

The development of new and improved particle-based drug delivery is underpinned by an enhanced ability to engineer particles with high fidelity and integrity, as well as increased knowledge of their biological performance. Microfluidics can facilitate these processes through the engineering of spatiotemporally highly controlled environments using designed microstructures in combination with physical phenomena present at the microscale. In this review, we discuss microfluidics in the context of addressing key challenges in particle-based drug delivery. We provide an overview of how microfluidic devices can: (i) be employed to engineer particles, by providing highly controlled interfaces, and ..

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University of Melbourne Researchers

Frank Caruso Author

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Grants

Awarded by Australian Research Council

Funding Acknowledgements

This work was supported by the Australian Research Council under the Australian Laureate Fellowship scheme (F.C., FL120100030) and the Discovery Early Career Researcher Award (Y.Y., DE130100488), as well as the Australian Government through an International Postgraduate Research Scholarship (M.B.) and an Australian Postgraduate Award (M.B.).